Shapes of curves of pH-dependence of reactions.

Spectrophotometric Study of Stability Constants of Metal Complexes of Promethazine at Different Temperatures

The complexation reactions between Cu2+, Pd2+ and Ni2+ metal ions with promethazine (PM) in water or DMF were studied by the spectrophotometric methods at [(15, 25,35 and 45±0.1) °C]. The complexation process was optimized in terms of pH, temperature and contact time. The stoichiometry of the complex was found to be 1:1 (metal ion/ligand). The formation constants of the resulting complexes were...

pH dependence of the inhibition of yeast glyoxalase 1 by prophyrins

pH Dependence Study of the Kinetic Reaction of Bovine Carbonic Anhydrase with 2,2'-Dithiobispyridine in the Absence and Presence of Surfactants

The pH dependence study reveals that the Cys 206 sulphydryl group of bovine carbonicanhydrase in the native form is not exposed. During the reaction of 2,2'-dithiobispyridine (2-DTP) with the enzyme, there was no absorbance change recorded. In the presence ofsurfactants, the pH dependence profiles of the apparent second order rate constants, kapp, forthe reaction of 2-DTP with bovine carbonic a...

pH-dependent pKa values in proteins--a theoretical analysis of protonation energies with practical consequences for enzymatic reactions.

Because of their central importance for understanding enzymatic mechanisms, pK(a) values are of great interest in biochemical research. It is common practice to determine pK(a) values of amino acid residues in proteins from NMR or FTIR titration curves by determining the pH at which the protonation probability is 50%. The pH dependence of the free energy required to protonate this residue is th...

OPTIMAL NOZZLE SHAPES OF CO2-N2-H2O GASDYNAMIC LASERS

In an axisymmetric CO2-N2-H2O gas dynamic laser, let ? denote the intersection of the vertical plane of symmetry with the upper part of the (supersonic) nozzle. To obtain a maximal small signal gain, some authors have tested several families of curves for ?. To find the most general solution for ?, an application of Pontryagin’s principle led to the conjuncture that the optimal ? must consist o...